Mouse Model for Cough Mus musculus (Mouse) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by Ammonia water
  • Model Animal StrainsKM mice (SPF class), Male, 6~8W, 22~25g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period1 week
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  • Mouse Model for Cough Packages (Simulation)
  • Mouse Model for Cough Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

The mouse with fasting 12 h and free drinking water. The 28% ammonia solution was sprayed with an ultrasonic nebulizer for 5s, and the mice were removed immediately.
Record the cough within 2 min，slected the mouse in the 2 mins were more than 10 times cough.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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