Mouse Model for Embryo Implantation Dysfunction (EID) Mus musculus (Mouse) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by mifepristone and/or indomethacin
  • Model Animal StrainsKuming(KM) Mice after mating, female, healthy, body weight: about 30g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period2 weeks
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  • Mouse Model for Embryo Implantation Dysfunction (EID) Packages (Simulation)
  • Mouse Model for Embryo Implantation Dysfunction (EID) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

At 3rd day and the 4th day of pregnancy, mice were injected with 4.33 mg / kg indomethacin, twice daily for 2 days to establish the animal model of embryo implantation dysfunction, which was related to the inhibition of vascular permeability and the inhibition of decidua.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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