Mouse Model for Keratitis Mus musculus (Mouse) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by herpes virus infection
  • Model Animal StrainsBalb/c Mice(SPF), healthy, male, age: 4~6weeks, body weight:18g~20g.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Mouse Model for Keratitis Packages (Simulation)
  • Mouse Model for Keratitis Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

(4 ~ 6 weeks old female Balb / c mice (body weight 14 ~ 16g) by intraperitoneal injection of pentobarbital sodium at a dose of 45 mg / kg body weight, placed under a microscope, with 1 ml syringe needle cross The corneal epithelium was stained with 5 μl of 2x10 ^ 8 PFU / ml virus (HSV-1RE strain) on the surface of the corneal cornea.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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