Mouse Model for Melasma Mus musculus (Mouse) Disease model

Chloasma faciei; Yellow Speckle

Add to Cart Distributors
Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by injection of progesterone combined with ultraviolet irradiation
  • Model Animal StrainsKunming (KM) mice, female, body weight: about 30g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period6~8 weeks
Share your citation Upload your experimental result Review Leave a message
Loading...

Share a new citation as an author

Upload your experimental result

Review

Please attach serial No. on instruction manual

Contact us

Please fill in the blank.

Name*
Organization
Address
E-mail address*
Telephone
Inquiry*
Verification code* CheckCode
  • Mouse Model for Melasma Packages (Simulation)
  • Mouse Model for Melasma Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

10% sodium sulfide aqueous solution to remove the back of the mouse hair, naked skin area of 1.5cmx1.5cm. Daily intramuscular injection of 0.4% progesterone (5ml/Kg body weight);
at the same time with a wavelength of 320nm in the ultraviolet (UVB) irradiation for a period of 6~8 weeks.

Model evaluation

1. The pathological morphology of skin melanocytes
2. MDA and SOD activity assay
3. Detection of behavior experiment:Open field test and Tail flick test

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

Recommend products