Mouse Model for Schizophrenia (SZ) Mus musculus (Mouse) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by NMDA receptor antagonist (MK-801)
  • Model Animal StrainsKM mice (SPF class), Male, 6~8W, 22~25g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period1 week
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  • Mouse Model for Schizophrenia (SZ) Packages (Simulation)
  • Mouse Model for Schizophrenia (SZ) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

N- methyl -D- aspartate, NMDA receptor antagonist (MK-801) was dissolved in normal saline and injected intraperitoneally with MK-801 (0.6mg/kg) for continuous injection of 7 days.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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