Porcine Model for Kaschin-Beck Disease (KBD) Sus scrofa; Porcine (Pig) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by by T-2 toxin
  • Model Animal StrainsPorcine (Pig),Healthy,no sex limit
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Porcine Model for Kaschin-Beck Disease (KBD) Packages (Simulation)
  • Porcine Model for Kaschin-Beck Disease (KBD) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

"Experimental miniature pigs fed low selenium feed (with low selenium area with low selenium corn production into) a month later, according to the daily in their only add T 2 toxin, (a week, anhydrous ethanol as mother liquor, diluted stir in feed) when using the dose of 1.5 mg/kg body weight feeding 67 d, then 36 d, T 2 toxin in feed add 3, 6, 9 mg respectively. Another group of feed add sodium selenite."

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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