Rabbit Model for Cataract Oryctolagus cuniculus (Rabbit) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by traumatism
  • Model Animal StrainsBig ears white rabbit, healthy, male and female, weight 1.5-2.5kg.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Rabbit Model for Cataract Packages (Simulation)
  • Rabbit Model for Cataract Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

3 to 4 months of age healthy bruising blue rabbits, first with 0.5% atropine eye drops 2 times and compound care of thiophene eye drops eye drops 3 times, 30 min after intramuscular injection of ketamine and promethazine anesthesia And local anesthesia with 0.5% dexamethasone in the conjunctival sac. In the surgical microscope with a disposable 1ml syringe in the central part of the cornea piercing the cornea, and the needle with the lens before the capsule to open about 1mmX 1. 5 mm oval small mouth, and then the needle deep into the central lens, along the anterior wound Long axis direction several times. Surgery Bone capsule coated with antibiotic eye ointment. The intraocular lens was examined daily with a slit lamp microscope.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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