Rabbit Model for Osteoarthritis (OA) Oryctolagus cuniculus (Rabbit) Disease model

Ostarthritis; Ostearthritis; OA

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by drug injection
  • Model Animal Strainsears white rabbit, healthy, male and female, weight 1.5-2.5kg.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Rabbit Model for Osteoarthritis (OA) Packages (Simulation)
  • Rabbit Model for Osteoarthritis (OA) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

Inject papain, which is a proteolytic enzyme, into the knee and hip joints of a rabbit and carry out local immobilization to observe the articular cartilage degeneration.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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