Rabbit Model for Thermal Injury (TI) Oryctolagus cuniculus (Rabbit) Disease model

Skin thermal injury ; Thermal burn; Scald

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by high-voltage electrical
  • Model Animal StrainsBig ears white rabbit, healthy, male and female, weight 1.5-2.5kg.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Rabbit Model for Thermal Injury (TI) Packages (Simulation)
  • Rabbit Model for Thermal Injury (TI) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

Remove the rabbit two hind legs medial thigh,the area is around 6 cm X 8 cm, then instal copper electrode plates on both sides of the area (3 cm X 3 cm) and fix it, the entry is on the right and left is for export,electric strike under the anesthesia implement ,the shock time is 5 seconds, rated voltage 10 kV, the through current for the (2 + / - 0.15)A, skin resistance of 2500 ohms, quickly remove after shocking plate electrode.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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