Rat Model for Diet-Induced Obesity (DO) Rattus norvegicus (Rat) Disease model

DIO

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by high fat diet
  • Model Animal StrainsWistar Rats(SPF), healthy, half male and half female, body weight 180g~200g.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group(low,medium,high).
  • Modeling Period4-6 weeks
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  • Rat Model for Diet-Induced Obesity (DO) Packages (Simulation)
  • Rat Model for Diet-Induced Obesity (DO) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

Rats from milk feeding high fat forage (based feed formula is: 80%. 10% lard and 10% egg yolk powder), the other filled by weight of sucrose (2 g/kg body weight).Feed is limited to eat out, and water.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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