Rat Model for Functional Dyspepsia (FD) Rattus norvegicus (Rat) Disease model

Indigestion; Dyspepsia

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Overview
Properties
  • Prototype SpeciesHuman
  • Sourceinduced by irregular diet with dilute hydrochloric acid
  • Model Animal StrainsSD rats (SPF), male, healthy, body weight:190~210g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period3~6weeks
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  • Rat Model for Functional Dyspepsia (FD) Packages (Simulation)
  • Rat Model for Functional Dyspepsia (FD) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

Irregular diet and dilute hydrochloric acid feeding resulted in functional dyspepsia.
On the first day to feed, the second day fasting, free drinking water, at the same time in the water by adding 10mol/l per liter of hydrochloric acid 10ml, for 3~5 weeks.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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