Rat Model for Metabolic Syndrome (MS) Rattus norvegicus (Rat) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by high salt, high fat and high sugar diet
  • Model Animal StrainsSD rats (SPF class), Male, 4~6W, 180~200g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period8 weeks
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  • Rat Model for Metabolic Syndrome (MS) Packages (Simulation)
  • Rat Model for Metabolic Syndrome (MS) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

The rats were fed with high salt, high fat and high sugar diet (52.5% basic feed, 10% lard, 10% egg yolk powder, 2% cholesterol, 10% milk powder, 10% fructose, 5% edible salt, and 0.5% bile salt), continuous feeding for 8 weeks.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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