Rat Model for Preeclampsia (PE) Rattus norvegicus (Rat) Disease model

Pre-eclampsia

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by injection of L-NAME
  • Model Animal StrainsSD rats (SPF), female, pregnant for 18 days
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period3 weeks
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  • Rat Model for Preeclampsia (PE) Packages (Simulation)
  • Rat Model for Preeclampsia (PE) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

The 18 day of pregnancy in female rats were subcutaneously injected with L-nitro-arginine (L-NAME) for 4 days.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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