Rat Model for Thermal Injury (TI) Rattus norvegicus (Rat) Disease model

Skin thermal injury ; Thermal burn; Scald

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Overview
Properties
  • Prototype SpeciesHuman
  • SourceInduced by burnning
  • Model Animal StrainsWistar Rats(SPF), healthy, male, body weight 180g~200g.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Rat Model for Thermal Injury (TI) Packages (Simulation)
  • Rat Model for Thermal Injury (TI) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

"According to the dose of 30 mg/kg body weight by intraperitoneal injection of 3% sodium pentobarbital anesthesia in rats, according to the weight of abdominal skin, and then to the laboratory bench. The will be closer to the beaker of the heating water in rats, the article gauze soaked in hot water, to remove the gauze when the water temperature constant 99 degrees, flat out to stay hot parts immediately, with gauze timing after contact with the skin of rats.
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Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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